Dentinogenesis is the process of dentin formation in the tooth. The cell group of odontoblasts, also known as dentinoblasts, begin to exist as specialized cells from the eighth to ninth week of fetal life, cells have a cylindrical cytoplasm and begin to make dentine, histochemically cells are basophilic to the technique hematoxylin and eosin. Histologically, when an odontoblast prepares to make dentine, it accumulates many metachromatic granules that will later leave the cell and become a system of collagen fibers, it is just on them that the calcification is elaborated within an alkaline pH. The minerals that make the sequence of calcification are first the calcium (Ca) and later the mineral Phosphate. The researchers believe theoretically that the dicalcium phosphate compound is made. Subsequently higher biochemical and cellular processes of calcification are elaborated in the dentin matrix and in the later stages it is detected that it is just the peritubular dentin that the greater processes of calcification have experienced. The dentin has a level of calcification in its matrix and later in transcends to be a mature dentine. Dentin does not possess the level of mineralization of the enamel and in experimentally induced processes of decalcification resembles somewhat to the cartilage in its flexibility. Dentin does have precollagen (still immature and young) fibers that are sensitive to histochemical techniques of silver and collagen. Secondary dentin
This dentin is made after the dental eruption. It is known that pulp tissue constantly produces dentin as a reaction to the environment or irritants. Consequently there are dental organs in young individuals who have experienced more irritation and with it the Dental Age has been aging as long as the physical age of the individual is that of a teenager or even a young person. It is known that in the elderly patient the dentinal tubules are calcified reducing the pulp space and thus there is a certain incidence of increased natural pulp protection. Recommended bibliography
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